Vacuolar-sorting Protein SNF8 (SNF8) Peptide
SNF8
Reactivité: Mammifères
Hôte: Synthetic
BP, WB, IHC
N° du produit ABIN939010
Aperçu rapide pour Vacuolar-sorting Protein SNF8 (SNF8) Peptide (ABIN939010)
Antigène
SNF8
(Vacuolar-sorting Protein SNF8 (SNF8))
Origine
Mammifères
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
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Type de proteíne
- Synthetic
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Séquence
- GTVLAEDQLA QMSKQLDMFK TNLEEFASKH KQEIRKNPEF RVQFQDMCAT
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Attributs du produit
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A synthetic peptide for use as a blocking control in assays to test for specificity of Snf8 antibody,
Alternative Names: Snf8 control peptide, Snf8 antibody Blocking Peptide, Anti-Snf8 Blocking Peptide, SNF8, ESCRT-II complex subunit, homolog, S. cerevisiae Blocking Peptide, D11moh34 Blocking Peptide, MGC105799 Blocking Peptide, RGD1310144 Blocking Peptide, Snf8, Snf-8, Snf 8, Snf-8 Blocking Peptide, Snf 8 Blocking Peptide
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Indications d'application
- Optimal conditions should be determined by the investigator
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
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Buffer
- PBS
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Conseil sur la manipulation
- Avoid repeated freeze/thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20 °C long term.
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- SNF8 (Vacuolar-sorting Protein SNF8 (SNF8))
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Sujet
- Snf8 is required for degradation of both endocytosed EGF and EGFR, but not for the EGFR ligand-mediated internalization. It is a component of the endosomal sorting complex required for transport II (ESCRT-II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs. The MVB pathway mediates delivery of transmembrane proteins into the lumen of the lysosome for degradation. The ESCRT-II complex is probably involved in the recruitment of the ESCRT-III complex. The ESCRT-II complex may also play a role in transcription regulation by participating in derepression of transcription by RNA polymerase II, possibly via its interaction with ELL.
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Poids moléculaire
- 28 kDa
Antigène
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